a multiple sequence alignment editor written in Java. It is used widely in a variety of web pages (e.g. the EBI Clustalw server and the Pfam protein domain database) but is available as a general purpose alignment editor.
Usage
To list all executables provided by Jalview, run:
$ sbgrid-list jalview
Usage Notes
To use Jalview on OS X, you will need to install Java:
Use the following command to install this title with the CLI client:$ sbgrid-cli install jalview Available operating systems: Linux 64, OS X INTEL
Primary Citation*
A. M. Waterhouse, J. B. Procter, D. M. A. Martin, M. Clamp, and G. J. Barton. 2009. Jalview Version 2 - a multiple sequence alignment editor and analysis workbench. Bioinformatics. 25(9): 1189-1191.
In 1987, when Geoff Barton was a graduate student learning computational structural biology at the University of London, just 6000 protein sequences were known, but their numbers were rising exponentially, and it was becoming clear that they had commonalities. Sequences that yield valuable functions have staying power, so they are conserved throughout evolution. Finding these recurring patterns, however, required painstaking pencil and paper comparisons.
A page from Barton's lab book in around 1988. It shows a multiple sequence alignment produced automatically by his alignment software, printed out then coloured by hand to highlight conserved amino acid positions in the alignment. Secondary structure predictions are shown underneath the alignment and there are other features such as intron/exon boundaries shown for some of the sequences. "Doing things like this all …
Topic: Creating and analyzing multiple sequence alignments with the Jalview Desktop Application Presenter: Jim Procter, Ph.D., Jalview Coordinator, College of Life Sciences, University of Dundee Scotland, UK