Member Publications

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35 Member Publications for March 2025

Molecular model of TFIIH recruitment to the transcription-coupled repair machinery.
1. Nat Commun - published March 8, 2025
2. Paul T, Yan C, Yu J, Tsutakawa SE, Tainer JA, Wang D, Ivanov I
G-quadruplex-stalled eukaryotic replisome structure reveals helical inchworm DNA translocation.
1. Science - published March 7, 2025
2. Batra S, Allwein B, Kumar C, Devbhandari S, Brüning JG, Bahng S, Lee CM, Marians KJ, Hite RK, Remus D
Hierarchical Assembly of Conductive Fibers from Coiled-Coil Peptide Building Blocks.
1. ACS Nano - published March 7, 2025
2. Grosvirt-Dramen A, Urbach ZJ, Hurst PJ, Kwok CE, Patterson JP, Wang F, Hochbaum AI
Crystal structures of monomeric BsmI restriction endonuclease reveal coordinated sequential cleavage of two DNA strands.
1. Commun Biol - published March 7, 2025
2. Sieskind R, Missoury S, Madru C, Commenge I, Niogret G, Hollenstein M, Rondelez Y, Sauguet L, Haouz A, Legrand P, Delarue M
Energy filtering enables macromolecular MicroED data at sub-atomic resolution.
1. Nat Commun - published March 6, 2025
2. Clabbers MTB, Hattne J, Martynowycz MW, Gonen T
On the role of VP3-PI3P interaction in birnavirus endosomal membrane targeting.
1. Elife - published March 6, 2025
2. Zanetti FA, Fernandez I, Baquero E, Guardado-Calvo P, Ferrino-Iriarte A, Dubois S, Morel E, Alfonso V, Aguilera MO, Celayes ME, Polo LM, Suhaiman L, Galassi VV, Chiarpotti MV, Allende-Ballestero C, Rodriguez JM, Castón JR, Lijavetzky D, Taboga O, Colombo MI, Del Pópolo M, Rey FA, Delgui LR
Impacts of ribosomal RNA sequence variation on gene expression and phenotype.
1. Philos Trans R Soc Lond B Biol Sci - published March 6, 2025
2. Welfer GA, Brady RA, Natchiar SK, Watson ZL, Rundlet EJ, Alejo JL, Singh AP, Mishra NK, Altman RB, Blanchard SC
Pseudo-ring methodology to control the conformations of macrocycles.
1. Chemistry - published March 6, 2025
2. Diamandas M, Ou D, Huang B, Yudin AK
Broadly neutralizing antibodies targeting pandemic GII.4 variants or seven GII genotypes of human norovirus.
1. Sci Transl Med - published March 5, 2025
2. Park J, Lindesmith LC, Olia AS, Costantini VP, Brewer-Jensen PD, Mallory ML, Kelley CE, Satterwhite E, Longo V, Tsybovsky Y, Stephens T, Marchioni J, Martins CA, Huang Y, Chaudhary R, Zweigart M, May SR, Reyes Y, Flitter B, Vinjé J, Tucker SN, Ippolito GC, Lavinder JJ, Snijder J, Kwong PD, Georgiou G, Baric RS
Bispecific antibodies targeting the N-terminal and receptor binding domains potently neutralize SARS-CoV-2 variants of concern.
1. Sci Transl Med - published March 5, 2025
2. Rubio AA, Baharani VA, Dadonaite B, Parada M, Abernathy ME, Wang Z, Lee YE, Eso MR, Phung J, Ramos I, Chen T, El Nesr G, Bloom JD, Bieniasz PD, Nussenzweig MC, Barnes CO
New insights into the noncanonical inflammasome point to caspase-4 as a druggable target.
1. Nat Rev Immunol - published March 5, 2025
2. Elkayam E, Gervais FG, Wu H, Crackower MA, Lieberman J
Improving CryoEM maps of symmetry-mismatched macromolecular assemblies: A case study on the flagellar motor.
1. J Struct Biol - published March 5, 2025
2. Singh PK, Iverson TM
MicroED Structures of Fluticasone Furoate and Fluticasone Propionate Provide New Insights into Their Function.
1. Cryst Growth Des - published March 5, 2025
2. Lin J, Unge J, Gonen T
Bipartite binding of the intrinsically disordered scaffold protein JIP1 to the kinase JNK1.
1. Proc Natl Acad Sci U S A - published March 4, 2025
2. Orand T, Delaforge E, Lee A, Kragelj J, Tengo M, Tengo L, Blackledge M, Boeri Erba E, Davis RJ, Palencia A, Jensen MR
CODANIN-1 sequesters ASF1 by using a histone H3 mimic helix to regulate the histone supply.
1. Nat Commun - published March 4, 2025
2. Jeong TK, Frater RCM, Yoon J, Groth A, Song JJ
Multifunctional Hydrogel Electrolyte Synergizing with Free-Standing Cathode Enables Robust Aqueous Zinc Metal Batteries.
1. Small - published March 4, 2025
2. Gong P, Zhai S, Liu S, Chai S, Wang N, Li Y, Liu J
Covalent inhibition of the SARS-CoV-2 NiRAN domain via an active-site cysteine.
1. J Biol Chem - published March 4, 2025
2. Hernandez G, Osinski A, Majumdar A, Eitson JL, Antczak M, Pawłowski K, Niederstrasser H, Servage KA, Posner B, Schoggins JW, Ready JM, Tagliabracci VS
α-Catenin force-sensitive binding and sequestration of LZTS2 leads to cytokinesis failure.
1. J Cell Biol - published March 3, 2025
2. Wang Y, Yemelyanov A, Go CD, Kim SK, Quinn JM, Flozak AS, Le PM, Liang S, Gingras AC, Ikura M, Ishiyama N, Gottardi CJ
Multiomic spatial atlas shows deleted in malignant brain tumors 1 (DMBT1) glycoprotein is lost in colonic dysplasia.
1. J Pathol - published March 3, 2025
2. Green EH, Kotrannavar SR, Rutherford ME, Lunnemann HM, Kaur H, Heiser CN, Ding H, Simmons AJ, Liu X, Lacy DB, Washington MK, Shrubsole MJ, Liu Q, Lau KS, Sears CL, Coffey RJ, Drewes JL, Markham NO
Beyond First-Generation KRAS Inhibitors: BBO-8520 Tests the Dual Mechanism Hypothesis.
1. Cancer Discov - published March 3, 2025
2. Zhou Z, Westover KD
Members of the DIP and Dpr adhesion protein families use cis inhibition to shape neural development in Drosophila.
1. PLoS Biol - published March 3, 2025
2. Morano NC, Lopez DH, Meltzer H, Sergeeva AP, Katsamba PS, Rostam KD, Gupta HP, Becker JE, Bornstein B, Cosmanescu F, Schuldiner O, Honig B, Mann RS, Shapiro L
Electrostatics of salt-dependent reentrant phase behaviors highlights diverse roles of ATP in biomolecular condensates.
1. Elife - published March 3, 2025
2. Lin YH, Kim TH, Das S, Pal T, Wessén J, Rangadurai AK, Kay LE, Forman-Kay JD, Chan HS
Lipid Dysregulation in Tangier Disease: A Case Series and Metabolic Characterization.
1. J Clin Endocrinol Metab - published March 3, 2025
2. Semmler G, Baumgartner C, Metz M, Gensluckner S, Habisch H, Hofer H, März W, Offner F, Völkerer A, Petrenko O, Wernly B, Draxler-Dworzak S, Neyer M, Nigmann C, Greber-Platzer S, Esterbauer H, Madl T, Aigner E, Scherer T, Datz C
In-Cell Fast Photochemical Oxidation Interrogates the Native Structure of Integral Membrane Proteins.
1. Angew Chem Int Ed Engl - published March 3, 2025
2. Sun J, Saimi M, Rempel D, Cao Q, Chang ML, Li W, Gross ML
Adenosine deaminase and deoxyadenosine regulate intracellular immune response in C. elegans.
1. iScience - published March 2, 2025
2. Wernet ND, Tecle E, Sarmiento MB, Kuo CJ, Chhan CB, Baick I, Batachari LE, Franklin L, Herneisen A, Bhabha G, Ekiert DC, Hanna-Rose W, Troemel ER
Targeting Bottlenecks in Malaria Transmission: Antibody-Epitope Descriptions Guide the Design of Next-Generation Biomedical Interventions.
1. Immunol Rev - published March 1, 2025
2. Yoo R, Jore MM, Julien JP
Crystal structure of dihydroorotate dehydrogenase from Helicobacter pylori with bound flavin mononucleotide.
1. Acta Crystallogr F Struct Biol Commun - published March 1, 2025
2. Agarwal AA, Georgiades JD, Dranow DM, Lorimer DD, Edwards T, Barrett KF, Craig JK, Van Voorhis WC, Myler PJ, Smith CL
Torsional twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains.
1. Protein Sci - published March 1, 2025
2. Rosas-Lemus M, Minasov G, Brunzelle JS, Taha TY, Lemak S, Yin S, Shuvalova L, Rosecrans J, Khanna K, Seifert HS, Savchenko A, Stogios PJ, Ott M, Satchell KJF
Protein Data Bank Japan: Improved tools for sequence-oriented analysis of protein structures.
1. Protein Sci - published March 1, 2025
2. Bekker GJ, Nagao C, Shirota M, Nakamura T, Katayama T, Kihara D, Kinoshita K, Kurisu G
Architects of infection: A structural overview of SARS-related coronavirus spike glycoproteins.
1. Virology - published March 1, 2025
2. Hills FR, Geoghegan JL, Bostina M
Allium Macrostemon Bge. Attenuates the Cognitive Decline of Aging Mice by Enhancing BDNF/TrkB Pathway.
1. Food Sci Nutr - published March 1, 2025
2. Sheng R, Zhao M, Pu K, Zhou Y, Zeng L, Chen Y, Wang P, Liu X, Xu S
Coronavirus endoribonuclease antagonizes ZBP1-mediated necroptosis and delays multiple cell death pathways.
1. Proc Natl Acad Sci U S A - published March 1, 2025
2. Evdokimova M, Feng S, Caobi A, Moreira FR, Jones D, Alysandratos KD, Tully ES, Kotton DN, Boyd DF, Banach BS, Kirchdoerfer RN, Saeed M, Baker SC
Allosteric inhibition of the IZUMO1-JUNO fertilization complex by the naturally occurring antisperm antibody OBF13.
1. Proc Natl Acad Sci U S A - published March 1, 2025
2. Lu Y, Ikawa M, Tang S
Expression and Purification of SARS-related Spike Glycoproteins for Cryo-EM Analysis.
1. Curr Protoc - published March 1, 2025
2. Hills FR, Jorge F, Burga LN, Bostina M
A bivalent spike-targeting nanobody with anti-sarbecovirus activity.
1. J Nanobiotechnology - published March 1, 2025
2. Swart IC, Debski-Antoniak OJ, Zegar A, de Bouter T, Chatziandreou M, van den Berg M, Drulyte I, Pyrć K, de Haan CAM, Hurdiss DL, Bosch BJ, Oliveira S